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KMID : 0361120050190020219
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Korean Journal of Transplantation
2005 Volume.19 No. 2 p.219 ~ p.220
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Kidney Transplantation in a Patient with Idiopathic Thrombocytopenic Purpura
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안형준/Ahn HJ
손태일/김유선/한대석/Son TI/Kim YS/Han DS
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Abstract
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Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder characterized by the presence of IgG autoantibody against platelet, low platelet count, and bleeding disorders. Anecdotal experience of renal transplantation adopting the use of 2 weeks of steroids treatment, perioperative intravenous immunoglobulin, and simultaneous splenectomy in a patient with ITP was reported recently. However, advantage of these procedures is not yet confirmed. Recently, we performed a case of uneventful renal transplantation in a patient with ITP without immunoglobulin treatment and no splenectomy. Although platelet counts have been under normal limit after transplantation, the anti-platelet antibody converted to negative postoperatively and the graft function has been stable until now. Our case report raised the question about the use of perioperative immunoglobulin and splenectomy in these particular patient groups waiting for renal transplantation.
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